55687-19-9, 5-Chloroquinoxalin-2-ol is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step 3: 5-chloroquinoxalin-2(1H)-one (0.60 g, 3.32 mmol) was heated to 90 C. in phosphorus oxychloride (10 mL, 109 mmol) for 3 hours. The reaction was poured onto ice and extracted with ethyl acetate. The organic extracts were combined, dried (MgSO4), filtered and the solvent removed to give a dark brown solid. This material was adsorbed onto silica and purified by column chromatography, eluding with a gradient of 0-30% ethyl acetate in hexane to afford 2,5-dichloroquinoxaline as a white solid (210 mg, 32% Yield).
The synthetic route of 55687-19-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Wyeth; US2010/120778; (2010); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider