879-65-2, 2-Quinoxalinecarboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,879-65-2
3. Take a 50 mL round bottom flask.To which quinoxaline-2-carboxylic acid (175 mg, 1 mmol) andEDCI (230mg, 1.2mmol) andHOBT (176mg, 1.3mmol)Soluble in 20mL DMF solution,The ratio of the amounts of the three raw materials is 1:1.2:1.3.Compound D (308 mg, 1.2 mmol) was added after half an hour.Stir at room temperature and monitor with TLC.After the reaction was completed, the reaction solution was washed with water, 5% HCl, 5% Na?The organic phase was dried over anhydrous Na 2 SO 4 and evaporated under reduced pressure.The crude product was separated and purified by thin layer chromatography (PE: EA = 2:1) to afford objective compound 1.Product 1 was a pale yellow solid with a yield of 40%.
As the paragraph descriping shows that 879-65-2 is playing an increasingly important role.
Reference£º
Patent; Hefei University of Technology; Li Qingshan; Shen Bangnian; Li Yao; Ruan Banfeng; (19 pag.)CN109912574; (2019); A;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider