With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7712-28-9,3-(3-Hydroxyquinoxalin-2-yl)propanoic acid,as a common compound, the synthetic route is as follows.,7712-28-9
General procedure: In a typical reaction, AMA 2:3 (10mmol), the corresponding carboxylic acid (1mmol) and the alcohol (2ml) were mixed in the provided reaction glass tube equipped with a screw cap and magnetic agitation until a wet mixture was achieved. The reaction mixture was irradiated with microwaves (Anton Parr Monowave 300 reactor) at 120C for 10-25min. On cooling, the mixture was diluted with DCM (41mL), and filtered over celite. Then the filtrate was washed with Na2CO3 (ss) and water. The organic layer was dried over Na2SO4, filtered, and concentrated under reduced pressure to give the ester.
As the paragraph descriping shows that 7712-28-9 is playing an increasingly important role.
Reference£º
Article; Estrin, Dario; Fabian, Lucas; Gomez, Natalia; Moglioni, Albertina; Salvatori, Melina; Taverna Porro, Marisa; Turk, Gabriela; European Journal of Medicinal Chemistry; vol. 188; (2020);,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider