32601-86-8, 2-Chloro-3-methylquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: Methyl 4-hydroxybenzoate (42.1mmol, 6.4g) and K2CO3 (50.5mmol, 5.3g) were dissolved in DMF (150mL), the resulting solution was allowed to react at 85C for 12h. Compound 2a (23.5mmol, 5.0g) was added in batches, and the resulting mixture was allowed to react for additional 12hat the same condition. After completion of reaction, the reaction was quenched with cooled water (150mL) and extracted with EtOAc (2¡Á100mL). The combined organic phase was washed with brine, dried over anhydrous MgSO4, filtered, and concentrated in vacuum to afford the crude product, which was purified by silica gel flash chromatography (PE: EA=50:1, v:v) to afford 6.6g of 3a as oily semi-solid, yield 80%. ESI-MS m/z: 295.4 [M+H]+., 32601-86-8
32601-86-8 2-Chloro-3-methylquinoxaline 236276, aquinoxaline compound, is more and more widely used in various.
Reference£º
Article; Xia, Qiao-Hong; Hu, Wei; Li, Chen; Wu, Ji-Feng; Yang, Liang; Han, Xue-Mei; Shen, Yue-Mao; Li, Zhi-Yu; Li, Xun; European Journal of Medicinal Chemistry; vol. 124; (2016); p. 311 – 325;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider