879-65-2, 2-Quinoxalinecarboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
879-65-2, To a solution of quinoxaline-2-carboxylic acid 5 (0.2 g, 1.14 mmol) in dichloromethane was cooled to 0 C followed by addition of triethylamine (0.18 ml, 1.2 equiv) and ethylchloroformate (0.14 ml, 1.2 equiv) into it and stirred for 30 min. This reaction mixture was then transferred to a solution in another flask containing 5-(4-aminophenyl)-10,15,20-tripyridylporphyrin 7 (0.1 g, 0.158) dissolved in dichloromethane and triethylamine (0.18 ml, 1.2 equiv) at 0 C. Stirring continued for 1 h at the same temperature and allowed to reach at room temperature for another 1 h. After completion of the reaction, water (5 mL) was added into the reaction mixture and basified to pH ~ 8 with sodium carbonate and extracted with chloroform (3 ¡Á 25 mL). The solvent was evaporated and purified on a silica gel (100-200) column chromatography by using 5% methanol/chloroform to produce porphyrin 8 in good yield. (0.095 g, 76%). 1H NMR (400 MHz, DMSO-d6) delta: 10.20 (s, 1H), 9.85 (s, 1H), 9.00-8.90 (m, 8H), 8.79-8.78 (m, 5H), 8.32-8.21 (m, 5H), 8.13-8.07 (m, 6H), 7.99-7.77 (m, 3H), -2.93 (s, 2H). ESIMS m/z: calcd for C50H33N10O: 788 (M+), found: 789 (M+H).
879-65-2 2-Quinoxalinecarboxylic acid 96695, aquinoxaline compound, is more and more widely used in various.
Reference£º
Article; Kumar, Dalip; Chandra Shekar; Mishra, Bhupendra; Kurihara, Ryohsuke; Ogura, Maiko; Ito, Takeo; Bioorganic and Medicinal Chemistry Letters; vol. 23; 11; (2013); p. 3221 – 3224;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider