108229-82-9, 6-Bromo-2,3-dichloroquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of compound 1 (2.78 g, 0.01 mol) in acetonitrile (50 mL), anhydrous potassium carbonate (2.0 g) and thiophenol (1.10 g, 0.01 mol) was added. The reaction mixture was heated under reflux for 4 h. After completion of the reaction, the reaction mixture was filtered to remove the potassium carbonate, then the excess of acetonitrile was evaporated under reduced pressure and the residue obtained was dried and purified by a silica gel column chromatography (petroleum ether (60-80C)/ethyl acetate 5 : 0.1, v/v ) to give the product. Yield: 48%; (yellow powder): m.p. 139-141 C; IR (KBr, cm -1 ): 1593 (C=N). 1 H NMR (DMSO-d 6 , delta ,ppm): 7.52-7.77 (m, 8H, Ar-H). 13 C NMR (DMSO-d 6 , delta , ppm): 121.74-140.20 (12Ar-C), 153.83, 154.51(2C=N). MS (m/z), 350 (M + ; 32%), 351 (M + + 1;100%), 352 (M + + 2; 46%), 353 (M + + 3; 37%), 354(M + + 4; 13%). Analysis: calcd. for C 14 H 8 BrClN 2 S(351.65): C, 47.82; H, 2.29; N, 7.97; S, 9.12%;found: C, 48.04; H, 2.47; N, 8.13; S, 9.35%., 108229-82-9
The synthetic route of 108229-82-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Abbas, Hebat-Allah S.; Al-Marhabi, Aisha R. M.; Ammar, Yousry A.; Acta poloniae pharmaceutica; vol. 74; 2; (2017); p. 445 – 458;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider