With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2427-71-6,6-Chloro-2(1H)-quinoxalinone,as a common compound, the synthetic route is as follows.
EXAMPLE 6 1-Carboxymethyl-6-chloroquinoxaline-2,3(1H,4H)-dione In accordance with the procedure described in example 1 the title compound was prepared starting from 6-chloroquinoxalin-2(1H)-one (Heterocycles, 23, (1985), 143). M.p. 318-19 C. 1 H-NMR (DMSO-d6):delta4.88 (s, 2H), 7.30-7.40 (m, 3H), 12.25 (s, 1H), 13.32 (br.s, 1H). Analysis: Calculated for C10 H7 N2 ClO4: C, 47.17; H, 2.77; N, 11.00; Cl, 13.92%. Found: C, 47.12; H, 2.79; N, 10.96; Cl, 13.89%., 2427-71-6
The synthetic route of 2427-71-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Novo Nordisk A/S; US5166155; (1992); A;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider