Downstream synthetic route of 7251-61-8

7251-61-8 2-Methylquinoxaline 23686, aquinoxaline compound, is more and more widely used in various.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7251-61-8,2-Methylquinoxaline,as a common compound, the synthetic route is as follows.

7251-61-8, (a) Quinoxaline-2-carbaldehyde[00368] To a solution of Se02 (2.3 g, 20.9 mmol) and water (1 mL) in 1 ,4-dioxane (25 mL) at reflux was added 2-methylquinoxaline (2 g, 13.9 mmol) in 1 ,4-dioxane (4 mL). After refluxing for 4 h, the reaction mixture was filtered. The filtrate was concentrated and purified by column chromatography to give 500 mg of the desired product. LC-MS: m/z 159 (M+H+).

7251-61-8 2-Methylquinoxaline 23686, aquinoxaline compound, is more and more widely used in various.

Reference£º
Patent; SUNOVION PHARMACEUTICALS INC.; CAMPBELL, John, Emerson; HEWITT, Michael, Charles; JONES, Philip; XIE, Linghong; WO2011/150156; (2011); A2;,
Quinoxaline – Wikipedia
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