32601-86-8, 2-Chloro-3-methylquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Under the protection of nitrogen,Add 3-methyl-2-chloro-quinoxaline (1.78 g, 10 mmol) to a solution of 2-isopropylaminoethoxyethanol (5.88 g, 40 mmol) in N-methylpyrrolidone (100 mL).Heated to 190 C reflux for 15 h,The reaction was monitored by LC-MS, and the reaction mixture was completed. The reaction was cooled and ice water (100 mL) was added to the reaction mixture, which was extracted with ethyl acetate (50 mL*3), and the organic phase was mixed with water (100 mL) and saturated brine (100 mL*2) After washing,Dry over anhydrous sodium sulfate, filter, decompress the solvent under reduced pressure, and then purified by chromatography on silica gel column.Drying in vacuo gave 2.27 g of white solid compound VIII-1.Yield: 78.5%,
32601-86-8, The synthetic route of 32601-86-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Chengdu Yuandong Bio-pharmaceutical Co., Ltd.; Zhang Tao; Zeng Yanqun; Yan Shengyong; Wang Ying; (22 pag.)CN108774183; (2018); A;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider