7251-61-8, 2-Methylquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
7251-61-8, Selenium dioxide (7.69 g, 69.35mmol) was added to a mixture of 1,4-dioxane (60 mL) and H2O (2.5 mL) and heated to reflux. 2-Methylquinoxaline (5 g, 34.67 mmol) was dissolved in 1,4-dioxane (10 mL) and added dropwise to the heated solution. A colour change to red-brown was observed. After heating for 4 h the hot mixture was filtered through Celite and washed with 1,4-dioxane (2 ¡Á 25 mL). The filtrate was allowed to cool and remove the solvent by evaporation. Chromatography of the residue (EtOAc-cyclohexane, 1:5) gave 6 as yellow needles (4.34 g, 79%); Rf = 0.42 (EtOAc-cyclohexane 1:5); mp 98-100 C; 1H-NMR (400MHz, CDCl3) d = 10.29 (s, 1H, CHO), 9.43(s, 1H), 8.20-8.27 (m, 2H), 7.90-7.95 (m, 2H); 13C-NMR (100MHz, CDCl3) delta192.7 (CHO), 145.9, 144.9 (each C), 142.5 (CH), 141.9 (C), 132.9, 131.1, 130.5, 129.6 (each CH); LRMS (ESI): Found 159.0 [M+H]+, C9H7N2O requires 159.1.
The synthetic route of 7251-61-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Jarikote, Dilip V.; Li, Wei; Jiang, Tao; Eriksson, Leif A.; Murphy, Paul V.; Bioorganic and Medicinal Chemistry; vol. 19; 2; (2011); p. 826 – 835;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider