879-65-2, 2-Quinoxalinecarboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
879-65-2, General procedure: General Synthesis Procedure for Nuepsilon-modified Na-tertbutoxycarbonyl-L-lysine-tert- butylesters 3a – 8a. Na-tertbutoxycarbonyl-L-lysine-tert-butyiester (0.5 g, 1.65 mmol) and the carboxylic acid of the respective chromophore (1.65 mmol, 1 eq) were placed in a 50 ml two-necked round bottom flask and were dissolved in an- hydrous dichloromethane (25 ml) under argon atmosphere. The solution was cooled to 0 C in an ice bath and N-methyl-morpholine (0.4 ml, 3.64 mmol, 2.2 eq) and PyBOP (0.95 g, 1.82 mmol, 1.1 eq) were added. The reaction mixture was stirred for 16 h at room temperature. The solution was washed with 30 ml Na- HC03, the phases were separated and dried with MgS04. The solvent was re- moved under reduced pressure and the obtained oil was purified using flash column chromatography with ethyl acetate / petrol ether mixtures. The pure product was obtained as a foam..
The synthetic route of 879-65-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; UNIVERSITAET KONSTANZ; SUMMERER, Daniel; SCHMIDT, Moritz Johannes; WO2015/11081; (2015); A2;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider