879-65-2, 2-Quinoxalinecarboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
879-65-2, Examples 16-18:O-(1H-Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate (112 mg, 0.30 mmol), triethylamine (207 mul, 1.49 mmol) and the product of preparation 24 (80 mg, 0.25 mmol) were added to a solution of the appropriate carboxylic acid (RCOOH, 0.28 mmol) in acetonitrile (1 ml), and the reaction mixture was stirred at room temperature for 18 hours. It was then heated under reflux for a further 18 hours before being concentrated in vacuo. The residues were diluted with dichloromethane (20 ml), washed with saturated sodium carbonate (20 ml), passed through a hydrophobic membrane and concentrated in vacuo. Purification of the residue by HPLC using a Phenomenex Luna C18 system, eluting with water/acetonitrile/trifluoroacetic acid (5:95:0.5):acetonitrile, 95:5 to 5:95, afforded the title compounds.
The synthetic route of 879-65-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; PFIZER LIMITED; WO2006/123242; (2006); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider