With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.108229-82-9,6-Bromo-2,3-dichloroquinoxaline,as a common compound, the synthetic route is as follows.
108229-82-9, Method A: To a solution of thiophenol (2.20 g,0.02 mol) in acetonitrile (50 mL), anhydrous potassium carbonate (2.0 g) and compound 1 (2.78 g,0.01 mol) were added. The reaction mixture washeated under reflux for 3 h. After completion of thereaction, the reaction mixture was filtered to removethe potassium carbonate, then the excess of acetoni-trile was evaporated under reduced pressure and theresidue obtained was dried and purified by a silicagel column chromatography (petroleum ether (60-80 O C)/ethyl acetate 5 : 0.1, v/v) to give the product;yield: 68%.
108229-82-9 6-Bromo-2,3-dichloroquinoxaline 13799585, aquinoxaline compound, is more and more widely used in various fields.
Reference£º
Article; Abbas, Hebat-Allah S.; Al-Marhabi, Aisha R. M.; Ammar, Yousry A.; Acta poloniae pharmaceutica; vol. 74; 2; (2017); p. 445 – 458;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider