With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.39267-04-4,2,3-Dichloro-6-methoxyquinoxaline,as a common compound, the synthetic route is as follows.
Example B 2,3-Dicyano-6-methoxyquinoxaline A mixture of 31.1 g of 2,3-dichloro-6-methoxyquinoxaline, 14.7 g of sodium cyanide and 2.79 g of benzyltrimethylammonium chloride is stirred in 210 ml of DMSO at room temperature for 48 hours. With intensive stirring the reaction mixture is poured onto 520 ml of ice-water, stirred for an hour, and filtered with suction, and the solid product is washed with water. Drying at 40 C. gives 23.8 g (83% of theory) of pale gray crystals with the following formula MS (m/e): 211 [M+H]+, 233 [M+Na]+ H NMR (DMSO): 8.21 (d, 1H), 7.83 (dd, 1H), 7.68 (d, 1H), 4.02 (s, 3H), 39267-04-4
The synthetic route of 39267-04-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Heckmann, Heino; Metz, Hans Joachim; US2007/264600; (2007); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider