With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.50998-17-9,6-Bromoquinoxaline,as a common compound, the synthetic route is as follows.,50998-17-9
Take 1mmol cp-2-19,Dissolved in 10ml anhydrous acetonitrile,0.05 mmol of Pd (OAc) 2,0.1 mmol of P (O-Tolyl) 3 and 3 mmol of Et3N were added,Then add 1.5mmol 6-bromoquinoxaline, Ar gas protection reaction 12h, after the reaction filter,After the filtrate was evaporated to dryness, the methylene chloride was dissolved, washed with water, washed with saturated NaCl, treated with anhydrous MgSO4,Silica gel column (PE: EA 50: 1) to give the compound
The synthetic route of 50998-17-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Peking University; Fu, Hongzheng; Chen, Peng; (29 pag.)CN106543032; (2017); A;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider