With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.3476-89-9,1,2,3,4-Tetrahydroquinoxaline,as a common compound, the synthetic route is as follows.
24d. 1-Methyl-4-(2-nitro-phenyl)-1,2,3,4-tetrahydro-quinoxaline To a solution of 1,2,3,4-tetrahydroquinoxaline (60 mg, 0.403 mmol) in DMSO (2 mL) was add potassium tert-butoxide (91 mg, 0.81 mmol), followed by 2-fluoro-nitrobenzene (57 mg, 0.403 mmol). The reaction mixture was stirred at 80 C. for 16 h. The desired product was isolated via silica gel chromatography using 0% to 50% EtOAc in hexane as eluding solvent to afford 24d (49 mg, 45%) as radish foam. LC-MS ESI m/z 270 [M+H]+., 3476-89-9
As the paragraph descriping shows that 3476-89-9 is playing an increasingly important role.
Reference£º
Patent; Tuerdi, Huji; Chao, Hannguang J.; Qiao, Jennifer X.; Wang, Tammy C.; Gungor, Timur; US2005/261244; (2005); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider