With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34117-90-3,3-Chloroquinoxalin-2-amine,as a common compound, the synthetic route is as follows.
Step B – Synthesis of Int-21BInt-21 A (1.20 g, 6.7 mmol) was combined with 1-phenyl-3-bromopropane-1,2-dione (1.67 g, 7.4 mmol, prepared as a yellow oil by bromination in CHCl3 at 50 C, followed by chromatography) in THF (10 mL) and ether (15 mL). The mixture was stirred 18 h, concentrated, treated with ethanol (40 mL), heated at 90 C for 72 h, and allowed to cool.Concentration, addition of methanol (10 mL), and filtration gave Int-21B as a brown solid., 34117-90-3
As the paragraph descriping shows that 34117-90-3 is playing an increasingly important role.
Reference£º
Patent; SCHERING CORPORATION; HARRIS, Joel, M.; NEUSTADT, Bernard, R.; STAMFORD, Andrew, W.; WO2011/60207; (2011); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider