83570-42-7, 1-(Quinoxalin-6-yl)ethanone is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
83570-42-7, To a stirred solution of 1-(quinoxalin-6-yl)ethan-1-one (0.8 g,4.65 mmol) in dry methanol (20 mL) at 0 C, NaBH4 (0.36 g, 9.30 mmol) was added portion wise and the resulting mixture was stirred for 1 h. After completion of the reaction (monitored by TLC), the mixture was quenched with ice cold water and the aqueous layer was extracted with DCM (2 x 40 mL). The combined organic layer was washed with water (20 mL), dried over anhydrous Na2S04 and concentrated under vacuum. The resulting crude material was forwarded to the next step without any further purification. Yield: 75% (600 mg, dark brown liquid). 1H NMR (400 MHz, DMSO-cfe): delta 8.91-8.89 (m, 2H), 8.03 (t, J = 1 1.6 Hz, 2H), 7.87-7.86 (m, 1 H), 5.49 (d, J = 5.9 Hz, 1 H), 4.98-4.97 (m, 1 H), 1.42 (d, J = 8.6 Hz, 3H). LCMS: (Method A) 175.0 (M+H), Rt. 1.89 min, 95.0% (Max).
83570-42-7 1-(Quinoxalin-6-yl)ethanone 22631249, aquinoxaline compound, is more and more widely used in various fields.
Reference£º
Patent; ASCENEURON S.A.; QUATTROPANI, Anna; KULKARNI, Santosh S.; GIRI, Awadut Gajendra; (134 pag.)WO2019/37860; (2019); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider