49679-45-0, Ethyl 3-chloroquinoxaline-2-carboxylate is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
49679-45-0, Step G (Compound 7) [00142] Compound 6 (1.6 g. ) was dissolved in ethanol (32.0 ml. ). The reaction mixture was cooled to approximately-50 degrees via an acetone/dry ice bath. Ammonia (g) was bubbled into the solvent for approximately 30 seconds and the glass vessel was capped. The bath was removed and the reaction mixture was allowed to gradually rise to room temperature where it was stirred overnight. The reaction mixture was re-cooled to-50 degrees (as above) and the glass vessel was opened. After allowing to warm to room temperature, the solid product was collected by filtration. After washing with a small amount of cool ethanol, the product was dried under reduced pressure. Yield: 720 mg. , approximately 52%. 1H NMR (500 MHz, CDC13) 5 8.16 (d, 1H), 8.08 (d, 1H), 7.97-7. 87 (m, 2H).
As the paragraph descriping shows that 49679-45-0 is playing an increasingly important role.
Reference£º
Patent; VERTEX PHARMACEUTICALS INCORPORATED; WO2005/56547; (2005); A2;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider