879-65-2,879-65-2, 2-Quinoxalinecarboxylic acid is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 67QUINOXALINE-2-CARBOXYLIC ACID [(R)-1-(2-FLUORO-4-METHANESULFONYLAMINO-5-METHYLPHENYL)ETHYL]AMIDE To a stirred solution of quinoxaline-2-carboxylic acid (26 mg, 0.15 mmol), N-[4-((R)-1-aminoethyl)-5-fluoro-2-methylphenyl]methanesulfonamide hydrochloride (35 mg, 0.12 mmol), and N,N,N’,N’-tetramethyl-O-(7-azabenzotriazol-1-yl)uronium hexafluorophosphate (56 mg, 0.15 mmol) in N,N-dimethylformamide (0.5 mL) was added N,N-diisopropylethylamine (80 mg, 0.6 mmol). A catalytic amount of DMAP was added, and the reaction was stirred at room temperature for 16 hours. The reaction mixture was concentrated down to a solid. The crude product was suspended in MeOH and filtered, and the filtrate purified by HPLC to give the title compound (25.0 mg, 49%) as an off-white solid. m/z=403.1 (M+1), r.t. 2.83 min. 1H NMR (400 MHz; d6-DMSO) delta 9.43 (1H, s), 9.39 (1H, d), 8.30-8.26 (1H, m), 8.22-8.18 (1H, m), 8.03-7.97 (2H, m), 7.45 (1H, d), 7.11 (1H, d), 5.49-5.39 (1H, m), 3.02 (3H, s), 2.24 (3H, s), 1.57 (3H, d).
As the paragraph descriping shows that 879-65-2 is playing an increasingly important role.
Reference£º
Patent; PFIZER INC.; RENOVIS, INC.; US2012/88746; (2012); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider