108229-82-9, 6-Bromo-2,3-dichloroquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of compound 1 (2.78 g, 0.01 mol) in acetic acid (50 mL), o-phenylenediamine (1.62 g,0.015 mol) was added and the reaction mixture was refluxed for 7 h. After completion of the reaction, the reaction mixture was cooled and the precipitate that formed was filtered, dried, crystallized fromethanol and purified by column chromatography using an elution system chloroform : methanol (10 :0.3, v/v) to give the product. Yield: 77%; (yellow powder): m.p. over 300C; IR (KBr, cm -1 ): 3182, 3112 (2NH), 1605 (C=N).1 H NMR (DMSO-d 6 , delta , ppm): 7.30-7.96 (m, 7H, Ar-H), 11.63, 11.70 (2s, br, 2H, 2NH; exchangeablewith D 2 O). 13 C NMR (DMSO-d 6 , delta , ppm): 114.43-143.23 (12Ar-C), 144.88, 145.03 (2C=N). MS(m/z), 312 (M + ; 100%), 313 (M + + 1; 23%), 314 (M ++ 2; 99.9%). Analysis: calcd. for C 14 H 9 BrN 4(313.15): C, 53.70; H, 2.90; N, 17.89%; found: C,53.92; H, 2.79; N, 18.04%., 108229-82-9
The synthetic route of 108229-82-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Abbas, Hebat-Allah S.; Al-Marhabi, Aisha R. M.; Ammar, Yousry A.; Acta poloniae pharmaceutica; vol. 74; 2; (2017); p. 445 – 458;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider