With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2213-63-0,2,3-Dichloroquinoxaline,as a common compound, the synthetic route is as follows.
EXAMPLE 21Preparation of Compound 59Step A – Synthesis of lnt-21AInt-19A (4.0 g, 20 mmol) was combined with NH4CI (5.4 g, 100 mmol) and 27% ammonia (32 mL) in isopropanol (40 mL). The mixture was heated in a sealed vessel for 20 h at 80 C, allowed to cool, and partitioned with CH2Cl2 and water. Washing with brine, drying (MgSO4), and concentration gave Int-21 A as a yellow solid., 2213-63-0
As the paragraph descriping shows that 2213-63-0 is playing an increasingly important role.
Reference£º
Patent; SCHERING CORPORATION; HARRIS, Joel, M.; NEUSTADT, Bernard, R.; STAMFORD, Andrew, W.; WO2011/60207; (2011); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider