With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.34117-90-3,3-Chloroquinoxalin-2-amine,as a common compound, the synthetic route is as follows.
General procerure: A solution of compound 14 or 3 (10 mmol) in pyridine (10 mL) was refluxed for 6 h. After cooling, it was poured on ice/water (200 mL) and acidified with diluted HCl (pH = 6) the product extracted by ethyl acetate (100 ¡Á 3). Solution of ethyl acetate dried over sodium acetate anhydrous (50 g) for 2 h, and then the solid is filtered off. A solution of ethyl acetate is evaporated under reduced pressure and crystals are collected., 34117-90-3
34117-90-3 3-Chloroquinoxalin-2-amine 817274, aquinoxaline compound, is more and more widely used in various fields.
Reference£º
Article; Galal, Shadia A.; Abdelsamie, Ahmed S.; Tokuda, Harukuni; Suzuki, Nobutaka; Lida, Akira; Elhefnawi, Mahmoud M.; Ramadan, Raghda A.; Atta, Mona H.E.; El Diwani, Hoda I.; European Journal of Medicinal Chemistry; vol. 46; 1; (2011); p. 327 – 340;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider