6298-37-9, Quinoxalin-6-amine is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,6298-37-9
[0171] To a solution of NaOCH3 (3.35 g, 62.07 mmol, 5.0 eq) in MeOH (60 mL), was added quinoxalin-6-amine (1.8 g, 12.41 mmol, 1.0 eq) and (HCHO)n (558.6 mg, 18.62 mmol, 1.5 eq). The mixture was heated to 50 C overnight. After cooling, NaBH4 (943.5 mg, 24.83 mmol, 2.0 eq) was added portwise, and the mixture was stirred at RT for 2 h. The resulting mixture was concentrated and the residue was dissolved in EtOAc, washed with water (3 times), dried over Na2S04 and concentrated under vacuo. The crude product was purified by chromatograph on silica gel (PE:EA = from 5: 1, to 0: 1, gradient ) to give the product (700 mg, yield: 35.5%); LC/MS: m/z (M++l) = 160.
The synthetic route of 6298-37-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; PHARMARESOURCES (SHANGHAI) CO., LTD.; CHEN, Ping; ZHOU, Ding; SHAO, Shaoping; CAI, Zhen-wei; WO2013/6792; (2013); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider