With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.55687-02-0,6-Bromo-2-chloroquinoxaline,as a common compound, the synthetic route is as follows.
The title compound was prepared from 6-Bromo-2-chloro-quinoxaline (3 g, 12.32 mmol) using the method applied for example 5 with the following exceptions: (1 ) in step 1 , 1-Methyl-1-phenyl-ethylamine (1.99 g, 14.72 mmol) was used instead of (R)-1 -(3-Fluoro-phenyl)-ethylamine and Nu,Nu-Diisopropylethylamine (8.4 mL, 6.23 g, 48.23 mmol) was used instead of trimethylamine (2) Title product was isolated as the free base. Yield of final step: 0.04 g (41 %)., 55687-02-0
The synthetic route of 55687-02-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SENTINEL ONCOLOGY LIMITED; BOYLE, Robert George; WALKER, David Winter; (166 pag.)WO2016/170163; (2016); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider