76982-23-5, 5-Bromoquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
76982-23-5, A mixture of 5-bromoquinoxaline (300 mg, 1.43 mmol, 1 eq), potassium [2- (benzyloxy)ethyl]-trifluoroboranuide (695 mg, 2.87 mmol, 2 eq), Pd(OAc)2 (65 mg, 0.29 mmol, 0.2 eq), Butyldi-l-adamantylphosphine (103 mg, 0.29 mmol, 0.2 eq) and Cs2C03 (1169 mg, 3.59 mmol, 2.5 eq) in Toluene (4 mL) and H20 (1 mL) was stirred overnight at 100 C. The reaction was quenched with water and extracted with EtOAc. The resulting mixture was concentrated under reduced pressure. The residue was purified by silica gel column chromatography, eluted with petroleum ether/EtOAc to afford 5-[2-(benzyloxy)ethyl]quinoxaline (321 mg, 85%) as a yellow oil. LCMS: m/z = 265.1 [M+H]+.
The synthetic route of 76982-23-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; PIPELINE THERAPEUTICS, INC.; XIONG, Yifeng; SCHRADER, Thomas; CHEN, Austin; ROPPE, Jeffrey Roger; BACCEI, Jill Melissa; BRAVO, Yalda; (199 pag.)WO2019/241131; (2019); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider