55687-02-0, 6-Bromo-2-chloroquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
6-bromo, 2-chloroquinoxaline (0.700 g, 2.8 mmol) and Triethylamine (0.87 g, 8.6 mmol) were dissolved in DMSO (15 mL) at room temperature and (f?)-1-(3-Fluoro-phenyl)- ethylamine hydrochloride (0.400 g, 2.8 mmol) was added. The reaction mixture was stirred at RT for 16 hours. After completion of reaction (confirmed by TLC), water (10OmL) was added to the reaction mixture and it was extracted with ethyl acetate (50 mL x 3). The organic layer was washed with water (15 mL), brine (15 mL), and was then dried over Na2SO4. The organic layer was concentrated in vacuo to afford the crude product.The crude product was adsorbed on silica gel and was purified by column chromatography using neutral silica gel of 60-120 mesh size. Methanol (1-1.5 %) was used as a gradient in DCM for elution of the title compound as a solid (0.35 g, 36%)., 55687-02-0
The synthetic route of 55687-02-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SENTINEL ONCOLOGY LIMITED; BOYLE, Robert, George; WALKER, David, Winter; WO2010/136755; (2010); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider