108229-82-9, 6-Bromo-2,3-dichloroquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of compound 1 (2.78 g, 0.01 mol) in DMF (50 mL), 4-(trifluoromethyl)aniline (1.61 g, 0.01 mol) was added. The reaction mixture was refluxed for 24 h. After completion of the reaction, the reaction mixture was poured onto crushed ice with stirring. Then, the solid residue that formed was filtered, washed with water, dried and crystallized from petroleum ether (80-100C) to give 4. Yield: 40%; (brown powder): m.p. 157-159 O C;IR (KBr, cm -1 ): 3158 (NH), 1603 (C=N). 1 H NMR(DMSO-d 6 , delta , ppm): 7.25-7.82 (m, 7H, Ar-H), 9.71(s, br, 1H, NH; exchangeable with D 2 O). 13 C NMR(DMSO-d 6 , delta , ppm): 121.15-147.09 (12Ar-C, CF 3 ),152.69, 152.86 (2C=N). MS (m/z), 336 (M + -C 2 H 3 F 2 ; 100%), 401 (M + ; 88%), 402 (M + + 1; 60%),403 (M + + 2; 57%), 404 (M + + 3; 62%), 405 (M + + 4;52%). Analysis: calcd. for C 15 H 8 BrClF 3 N 3 (402.60):C, 44.75; H, 2.00; N, 10.44%; found: C, 44.61; H,2.26; N, 10.69%.
108229-82-9, 108229-82-9 6-Bromo-2,3-dichloroquinoxaline 13799585, aquinoxaline compound, is more and more widely used in various fields.
Reference£º
Article; Abbas, Hebat-Allah S.; Al-Marhabi, Aisha R. M.; Ammar, Yousry A.; Acta poloniae pharmaceutica; vol. 74; 2; (2017); p. 445 – 458;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider