With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.879-65-2,2-Quinoxalinecarboxylic acid,as a common compound, the synthetic route is as follows.
879-65-2, j. Quinoxaline-2-carboxylic Acid {(S)-3-methyl-1-[3-hydroxy-1-(1-oxy-pyridine-2-sulfonyl)-azepan-4-ylcarbamoyl]-butyl}amide To a solution of the compound of Example 1i (320 mg, 0.73 mmol) in CH2Cl2 was added triethylamine (0.15 mL, 1.09 mmol), EDC (140 mg, 0.73 mmol), HOBt (99 mg, 0.73 mmol) and quinoxaline-2-carboxylic acid (127 mg, 0.73 mmol). The reaction was stirred until complete by TLC analysis. Workup and column chromatography of the residue gave the title compound: MS(EI) 556 (M+).
As the paragraph descriping shows that 879-65-2 is playing an increasingly important role.
Reference£º
Patent; SmithKline Beecham Corporation; US6583137; (2003); B1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider