6298-37-9, Quinoxalin-6-amine is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,6298-37-9
Synthesis of 4-propvl-N-quinoxalin-6-vl-benzenesulfonamide, STX 958 (KRB01085) :; To a solution of 4n-propylbenzenesulphonyl chloride (142 mg, 0.651 mmol) in dichloromethane (4 mL) was added pyridine (125 uL, 1.55 mmol) and the mixture was stirred under N2 for 5 min, after which time 6-aminoquinoxaline (90 mg, 0.62 mmol) was added. The resulting mixture was stirred for 4 h at room temperature, then saturated NaHCO3 solution (10 mL) was added and the mixture was extracted into ethyl acetate (20 mL). The organic phase was washed with brine, dried (Na2SO4), filtered and evaporated to give a residue that was purified using flash chromatography to afford an off-white solid (190 mg, 94%), single spot at Rf 0.66 (ethyl acetate). mp 198. 4-198. 9C, HPLC purity 99+% (tR 2. 22 min in 10% water-acetonitrile).’H NMR (CDCI3) : 68. 77 (1H, d, J=1.7 Hz), 8.73 (1H, d, J=1.7 Hz), 8.00 (1H, d, J=8.9 Hz), 7.80 (2H, d, J=8.2 Hz), 7.71 (1 H, d, J=2.5 Hz), 7.59 (1H, dd, J=8.9, 2.5 Hz), 7.23 (2H, obscured under CHCl3), 2.57 (2H, t, J=7.6 Hz), 1.58 (2H, sextet, J=7.5 Hz), 0.87 (3H, t, J=7.4 Hz). LCMS: 326.24 (M- ). FAB-MS (MH+, C17H17N302S) : calcd 328.1119, found 328.1136.
As the paragraph descriping shows that 6298-37-9 is playing an increasingly important role.
Reference£º
Patent; STERIX LIMITED; WO2005/42513; (2005); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider