I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 32998-25-7, help many people in the next few years.Formula: C9H7ClN2O
In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Formula: C9H7ClN2O, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 32998-25-7, name is 2-Chloro-3-methoxyquinoxaline. In an article£¬Which mentioned a new discovery about 32998-25-7
AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE
The present invention provides aromatic nitrogen-containing 6-membered ring compounds having execellent PDE10 inhibitory activity. The present invention relates to an aromatic nitrogen-containing 6-membered ring compound represented by the following formula [I 0 ] or a pharmaceutically acceptable salt thereof, a method for preparing the same, and use of said compounds for PDE10 inhibitors, and a pharmaceutical composition comprising said compounds as an active ingredient: Formula [I 0 ] wherein: X 1 , X 2 and X 3 each independently are N or CH, and at least two of X 1 , X 2 and X 3 are N; A is *-CH=CH-, *-C(Alk)=CH-, *-CH 2 -CH 2 – or *-O-CH 2 – (* is a bond with R 1 ); Alk is a lower alkyl group; Ring B is an optionally substituted nitrogen-containing aliphatic heterocyclic group; R 1 is an optionally substituted nitrogen-containing heterocyclic group, a nitrogen-containing heterocyclic moiety of which is a moiety selected from the group consisting of quinoxalinyl, quinolyl, isoquinolyl, quinazolinyl, pyrazinyl, pyrimidinyl and a moiety thereof fused with a 5 to 6-membered aliphatic ring thereto; Y 0 is a group selected from the group consisting of the following (1) to (5): (1) an optionally substituted phenyl or an optionally substituted aromatic monocyclic 5 to 6-membered heterocyclic group; (2) an optionally substituted aminocarbonyl; (3) an optionally substituted amino lower alkyl; (4) -O-R 2 wherein R 2 is hydrogen, an optionally substituted lower alkyl, lower cycloalkyl, aliphatic monocyclic 5 to 6-membered heterocyclic group, or Formula [AA]; (5) mono- or di-substituted amino; provided that, when Y 0 is mono- or di-substituted amino, the nitrogen-containing heterocyclic moiety of R 1 is not quinoxalinyl or quinolyl
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 32998-25-7, help many people in the next few years.Formula: C9H7ClN2O
Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1117 | ChemSpider