80636-30-2, Name is 3,3-Dimethyl-3,4-dihydroquinoxalin-2(1H)-one, belongs to quinoxaline compound, is a common compound. SDS of cas: 80636-30-2In an article, once mentioned the new application about 80636-30-2.
Synthesis of novel quinoxaline derivatives and its cytotoxic activities
Substituted dihydroquinozalin-2-ones (1-16) have been synthesized easily by the use of copper-catalyzed coupling method. The reactions of 2-haloanilines with a variety of alpha-amino acids in the presence of copper (I) iodide gave corresponding 3-substituted dihydroquinozalin-2-ones in up to 86% yield. Some new quinoxalin-2-ones (2, 4, 5, 13 and 16) have moderate cytotoxic activity toward HeLaS3 cell lines at 4.9-18.1 muM.
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Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N991 | ChemSpider