18514-76-6, Name is 5-Nitroquinoxaline, belongs to quinoxaline compound, is a common compound. category: quinoxalineIn an article, once mentioned the new application about 18514-76-6.
Palladium-Catalyzed C?C Ring Closure in alpha-Chloromethylimines: Synthesis of 1H-Indoles
The C-C ring closure of alpha-chloromethyl alkyl or aryl N-aryl imines catalyzed with 1 to 10 % Pd(OAc)2/P(p-tolyl)3 afford efficiently 2-aryl- and 2-alkyl-1H-indoles. The heterocyclization reaction involves the initial formation of [2-(arylimino)ethyl]palladium(II) chloride complexes with subsequent C-H activation of the aromatic amine ring. Readily or commercially available alpha-chloromethyl-aryl or -alkyl ketones are used as the precursors. Functionalized indoles at the benzene ring are obtained when the imines are derived from substituted anilines.
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Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N831 | ChemSpider