Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Quality Control of 2-Chloroquinoxaline. Introducing a new discovery about 1448-87-9, Name is 2-Chloroquinoxaline
Large-scale solvent-free chlorination of hydroxy-pyrimidines,-pyridines,- pyrazines and-amides using equimolar POCl3
Chlorination with equimolar POCl3 can be efficiently achieved not only for hydroxypyrimidines, but also for many other substrates such as 2-hydroxy-pyridines,-quinoxalines, or even-amides. The procedure is solvent-free and involves heating in a sealed reactor at high temperatures using one equivalent of pyridine as base. It is suitable for large scale (multigram) batch preparations.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Quality Control of 2-Chloroquinoxaline, you can also check out more blogs about1448-87-9
Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N713 | ChemSpider