Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 32601-86-8, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 32601-86-8
Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors
The synthesis and evaluation of a new series of IsoCombretaQuinolines (IsoCoQuines) 2 with a 2-substituted-quinoline in place of the 3,4,5-trimethoxyphenyl ring present in isoCA-4 and CA-4 are described. Most of these compounds displayed a potent cytotoxic activity (IC50< 10 nM) against a panel of five human cancer cell lines and inhibited tubulin assembly at a micromolar level. The most potent analogue 2b, having a 3-hydroxy-4-methoxyphenyl as B-ring, led to cell cycle arrest in G2/M phase. Docking studies indicate that 2b showed a binding mode comparable to those previously observed with quinazoline analogous (IsoCoQ) and with isoCA-4 at the colchicine binding site of tubulin. If you are interested in 32601-86-8, you can contact me at any time and look forward to more communication. Recommanded Product: 32601-86-8
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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1031 | ChemSpider