One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: 2-Chloro-3-methylquinoxaline, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 32601-86-8, Name is 2-Chloro-3-methylquinoxaline, molecular formula is C9H7ClN2
Facile and efficient regioselective synthesis of 1-(3?-substituted quinoxalin-2?-yl)-3-aryl/heteroaryl-5-methylpyrazoles
This report describes an efficient and practical approach for regioselective synthesis of 1-(3?-substituted quinoxalin-2?-yl)-3- aryl/heteroaryl-5-methylpyrazoles (3a-j). Reaction of 2-chloro-3-substituted quinoxalines (1) with 3(5)-methyl-5(3)-aryl-1H-pyrazoles (2) in the presence of sodium hydride furnished the title compounds in excellent yields with good levels of regioselectivity. The present protocol is superior to the existing method, which yielded a mixture of regioisomeric pyrazoles (I, II) and triazolo[4,3-a]quinoxalines (III). Supplemental materials are available for this article. Go to the publisher’s online edition of Synthetic Communications to view the free supplemental file.
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Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1008 | ChemSpider