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Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry
This study establishes the applicability of imine-based dynamic combinatorial chemistry to discover non-covalent ligands for RNA targets. We elucidate properties underlying the reactivity of arylamines and demonstrate target-guided amplification of tight binders in an amiloride-based dynamic library.
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Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N97 | ChemSpider