86-99-7, Name is 7-Chloroquinolin-4-ol, molecular formula is C9H6ClNO, Quality Control of 7-Chloroquinolin-4-ol, belongs to quinoxaline compound, is a common compound. In a patnet, author is Akbari, Mosayeb, once mentioned the new application about 86-99-7.
Efficient synthesis of novel 2-(2-chloroquinolin-3-yl)imidazo[1,2-a]pyridin-3-amine derivatives
An efficient method is applied for the synthesis of novel 2-(2-chloroquinolin-3-yl)-N-alkylimidazo[1,2-a]pyridin-3-amine derivatives. The method is based on a two-step approach from acetanilide, 2-chloro-3-formyl quinoline, 2-aminopyridine, and isocyanide under mild reaction conditions. In the first step, acetanilide forms 2-chloroquinoline-3-carbaldehyde in the presence of phosphoryl chloride. The synthesized 2-chloroquinoline-3-carbaldehyde takes part in a multicomponent reaction with 2-aminopyridine, and isocyanide in the presence of trimethylsilyl chloride. The reaction is facile and the products are synthesized in high isolated yields under mild reaction conditions.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 86-99-7 help many people in the next few years. Quality Control of 7-Chloroquinolin-4-ol.
Reference:
Quinoline – Wikipedia,
,Quinoline | C9H7N – PubChem