Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Yang, Wan-Wan, once mentioned the application of 90-52-8, Name is 8-Amino-6-methoxyquinoline, molecular formula is C10H10N2O, molecular weight is 174.1992, MDL number is MFCD00672902, category is quinoxaline. Now introduce a scientific discovery about this category, Category: quinolines-derivatives.
Catalyst- and Additive-Free Annulation of Ynediones and (Iso)Quinoline N-Oxides: An Approach to Synthesis of Pyrrolo[2,1-a]Isoquinolines and Pyrrolo[1,2-a]Quinolines
A simple and effective annulation of ynediones and (iso)quinoline N-oxides was developed to afford various functionalized pyrrolo[2,1-a]isoquinolines and pyrrolo[1,2-a]quinolines in moderate to excellent yields. This protocol underwent a tandem [3 + 2] cycloaddition/ring-opening/N-nucleophilic addition, which exhibited high regioselectivity, broad substrate tolerance, and atom economy under catalyst-, additive-free, and air conditions. Moreover, indolizine was also successfully prepared using pyridine N-oxide.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 90-52-8, Category: quinolines-derivatives.
Reference:
Quinoline – Wikipedia,
,Quinoline | C9H7N – PubChem