In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Formula: C8H5N3O2, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 18514-76-6, name is 5-Nitroquinoxaline. In an article£¬Which mentioned a new discovery about 18514-76-6
Synthesis and antiserotonin activity of ethyl 5-O-(4-methylpiperazin-1-ylacetyl)-2-methylindole-3-carboxylates and 3-(4-methyl-1-piperazinylglyoxyl)indoles
Ethyl-5-O-chloroacetyl-2-methylindole-3-carboxylates (2a-e) have been synthesised by the reaction of ethyl 5-hydroxy-2-methylindole-3-carboxylates (1a-e) with chloroacetyl chloride in dry benzene containing triethylamine.These indoles (2a-e) on condensation with methylpiperazine in dry acetone in the presence of anhydrous K2CO3, afford ethyl 5-O-(4-methylpiperazin-1-ylacetyl)-2-methylindole-3-carboxylates (3a-e).Compounds 3a-e are converted into their oxalate derivatives (4a-e).Indole-3-glyoxyl chlorides (6a-e) have been prepared from appropriate indoles (5a-e) byreaction with oxalyl chloride in dry ether. these derivatives on condensation with methylpiperazine yield 3-(4-methyl-1-piperazinylglyoxylyl)indoles (7a-e) wich are converted into oxalate salts (8a-e).Compounds 4a-e and 8a-e have been screened for their antiserotonin activity.Only compound 4d is found to exhibit antiserotonin activity.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 18514-76-6, help many people in the next few years.Formula: C8H5N3O2
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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N896 | ChemSpider