In heterogeneous catalysis, catalysts provide a surface to which reactants bind in a process of adsorption. The reactant in an enzyme-catalyzed reaction is called a substrate. 857890-39-2, Name is Lenvatinib Mesylate, molecular formula is , belongs to quinoxaline compound. In a document, author is Mu, Xu-Yang, Recommanded Product: 857890-39-2.
Synthesis of 2-ethoxycarbonylthieno[2,3-b]quinolines in biomass-derived solvent gamma-valerolactone and their biological evaluation against protein tyrosine phosphatase 1B
A series of 2-ethoxycarbonylthieno[2,3-b]quinolines were synthesized in the bio-derived green solvent gamma-valerolactone (GVL) and evaluated for their inhibitory activities against PTP1B, the representative compound 6a displayed an IC50 value of 8.04 +/- 0.71 mu M with 4.34-fold preference over TCPTP. These results provided novel lead compounds for the design of inhibitors of PTP1B as well as other PTPs.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 857890-39-2, in my other articles. Recommanded Product: 857890-39-2.
Reference:
Quinoline – Wikipedia,
,Quinoline | C9H7N – PubChem