Discovery of 2,3-Dichloroquinoxaline

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 2213-63-0, help many people in the next few years.Application In Synthesis of 2,3-Dichloroquinoxaline

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Application In Synthesis of 2,3-Dichloroquinoxaline, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 2213-63-0, name is 2,3-Dichloroquinoxaline. In an article，Which mentioned a new discovery about 2213-63-0

Ligand/PTC-free intramolecular Heck reaction: Synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo

A series of 1,3-disubstituted pyrrolo[2,3-b]quinoxalines has been designed for the potential inhibition of PDE4 without inhibiting luciferase. A ligand/PTC (phase transfer catalyst) free intramolecular Heck cyclization strategy was used to prepare these compounds, some of which showed significant inhibition of PDE4B (IC50 ? 5-14 muM) and growth inhibition of oral cancer cells (CAL 27) but not inhibition of luciferase in vitro. They also showed acceptable safety profiles but no apoptosis in zebrafish embryos.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 2213-63-0, help many people in the next few years.Application In Synthesis of 2,3-Dichloroquinoxaline

Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1262 | ChemSpider