1448-87-9, Name is 2-Chloroquinoxaline, belongs to quinoxaline compound, is a common compound. Recommanded Product: 1448-87-9In an article, once mentioned the new application about 1448-87-9.
A highly practical and convenient halogenation of fused heterocyclic N-oxides
A novel, simple and practical method for the regioselective halogenation of fused heterocyclic N-oxides has been developed. It employs Vilsmeier reagent, generated in situ by POX3and DMF, as both the activating agent and the nucleophilic halide source. The method is amenable across a broad range of substrates, including quinolines, isoquinolines and the diazine N-oxides, possessing a variety of substitution patterns. Furthermore, all of the reagents associated are cheap and easy to obtain. The potential extension of this method to a one-pot oxidation/halogenation sequence that obviates the need for isolation of the N-oxide intermediates is also presented.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 1448-87-9
Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N712 | ChemSpider