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Assembly of Primary (Hetero)Arylamines via CuI/Oxalic Diamide-Catalyzed Coupling of Aryl Chlorides and Ammonia
A general and practical catalytic system for aryl amination of aryl chlorides with aqueous or gaseous ammonia has been developed, with CuI as the catalyst and bisaryl oxalic diamides as the ligands. The reaction proceeds at 105-120C to provide a diverse set of primary (hetero)aryl amines in high yields with various functional groups.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.name: Quinoxalin-6-amine, you can also check out more blogs about6298-37-9
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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N79 | ChemSpider