Synthetic Route of 98416-72-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.98416-72-9, Name is 6-Bromo-2-chloro-3-methylquinoxaline, molecular formula is C9H6BrClN2. In a Patent,once mentioned of 98416-72-9
1-ARYL-4-METHYL-[ 1,2,4]TRIAZOLO[4,3-a]QUINOXALINE DERIVATIVES
The present invention relates to novel 1-aryl-4-methyl-[1,2,4]triazolo[4,3-a]-quinoxaline derivatives as inhibitors of phosphodiesterase 2 (PDE2) and to a lesser extent of phosphodiesterase 10 (PDE10) or as inhibitors of both, phosphodiesterases 2 and 10. The invention is also directed to harmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which PDE2 is involved, or disorders in which both PDE2 and PDE10 are involved, such as neurological and psychiatric disorders, and endocrinological or metabolic diseases. The present invention also relates to radiolabeled compounds which may be useful for imaging and quantifying the PDE2 enzyme in tissues, using positron- emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such com-pounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds.
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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1990 | ChemSpider