In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Application In Synthesis of Quinoxalin-5-ol, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 17056-99-4, name is Quinoxalin-5-ol. In an article，Which mentioned a new discovery about 17056-99-4
Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis
Persistent bacteria, including persister cells within surface-attached biofilms and slow-growing pathogens lead to chronic infections that are tolerant to antibiotics. Here, we describe the structure-activity relationships of a series of halogenated phenazines (HP) inspired by 2-bromo-1-hydroxyphenazine 1. Using multiple synthetic pathways, we probed diverse substitutions of the HP scaffold in the 2-, 4-, 7-, and 8-positions, providing critical information regarding their antibacterial and bacterial eradication profiles. Halogenated phenazine 14 proved to be the most potent biofilm-eradicating agent (?99.9% persister cell killing) against MRSA (MBEC < 10 muM), MRSE (MBEC = 2.35 muM), and VRE (MBEC = 0.20 muM) biofilms while 11 and 12 demonstrated excellent antibacterial activity against M. tuberculosis (MIC = 3.13 muM). Unlike antimicrobial peptide mimics that eradicate biofilms through the general lysing of membranes, HPs do not lyse red blood cells. HPs are promising agents that effectively target persistent bacteria while demonstrating negligible toxicity against mammalian cells. I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 17056-99-4, help many people in the next few years.Application In Synthesis of Quinoxalin-5-ol
Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N111 | ChemSpider