Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 2-Chloro-3-methylquinoxaline. Introducing a new discovery about 32601-86-8, Name is 2-Chloro-3-methylquinoxaline
The present invention provides a tri-substituted pyrimidine compound having an excellent PDE10 inhibitory activity. The present invention relates to a tri-substituted pyrimidine compound represented by the following formula [I0] or a pharmaceutically acceptable salt thereof, a method for preparing the same, and use of said compound for PDE10 inhibitor, and a pharmaceutical composition comprising said compounds as an active ingredient: wherein: either one of X1 and X2 is N, and the other of X1 and X2 is CH; A is *-CH?CH?, *-C(Alk)=CH?, *-CH2?CH2? or *-O?CH2? (* is a bond with R1); Alk is a lower alkyl group; Ring B is an optionally substituted nitrogen-containing aliphatic heterocyclic group; R1 is an optionally substituted quinoxalinyl or an optionally substituted quinolyl; Y0 is mono- or di-substituted amino group, or a pharmaceutically acceptable salt thereof.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 2-Chloro-3-methylquinoxaline, you can also check out more blogs about32601-86-8
Reference£º
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1001 | ChemSpider