Day: May 17, 2021

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Computed Properties of C8H8N4, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 6640-47-7, name is Quinoxaline-2,3-diamine. In an article，Which mentioned a new discovery about 6640-47-7

The invention belongs to the field of pharmaceutical chemistry, in particular relates to a toll-like receptor regulation has the effect of a compound, its preparation and use. The present invention provides a compound of the following formula X shown. The compounds of formula X can be used as the toll-like receptor modulators, its activity is high. In addition, compounds of the invention have high efficiency and low toxicity, anti-drug resistance and the like, it has clinical application value. And, the compounds of the invention of simple synthesis steps, therefore with greater economic value. (by machine translation)

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N247 | ChemSpider

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. category: quinoxaline, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 6298-37-9, name is Quinoxalin-6-amine. In an article，Which mentioned a new discovery about 6298-37-9

The present invention relates to a series of novel compounds, methods to prevent or treat viral infections in animals by using the novel compounds and to said novel compounds for use as a medicine, more preferably for use as a medicine to treat or prevent viral infections, particularly infections with RNA viruses, more particularly infections with viruses belonging to the family of the Flaviviridae, and yet more particularly infections with the Dengue virus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the novel compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of viral infections. The invention also relates to processes for preparation of the compounds.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N58 | ChemSpider

Related Products of 2379-56-8, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.2379-56-8, Name is 6-Nitroquinoxaline-2,3-dione, molecular formula is C8H3N3O4. In a Article，once mentioned of 2379-56-8

Some new 1,5-dihydro<1,2,4>ditriazolo<4,3-a:3',4'-c>quinoxaline-1,6-diones (IV) have been prepared and tested for their antiallergic, antimicrobial, antiprotozoal and anthelmintic activities.Compounds IVe,d,f are found to posess promising egg albumin-induced rat passive cutaneous anaphylaxis (PCA) activity by showing more than 90percent inhibition at 50 mg/kg dose

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1713 | ChemSpider

Related Products of 6639-87-8, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 6639-87-8, Name is 6-Nitroquinoxaline, molecular formula is C8H5N3O2. In a Article，once mentioned of 6639-87-8

As part of our continuing efforts to develop second generation photodynamic therapeutic agents [1], we synthesized three pentacyclic azine dyes that were designed with the aid of MNDO calculations to absorb visible light having wavelengths longer than 600 nm. Photophysical measurements for the azine dyes 1,4,8,11-tetraethyl-1,2,3,4,8,9,10,11,13- nonahydrodipyrazino[2,3-b:2′,3′-i]phenazinium acetate, 13, 1,4,8,11- tetraethyl-2,3,4,8,9,10,11,12,13-octahydro-13-methyldipyrazino[2,3-b:2′,3′- i]phenazinium iodide, 14, and 1,4,8,11,13-pentaethyl-2,3,4,8,9,10,11,12,13- octahydrodipyrazino[2,3-b:2′,3′-i]phenazinium iodide, 15, are highlighted by a 35 nm red shift in their absorption spectra and a 5-7 fold increase in their singlet oxygen quantum yield relative to tricyclic model compounds 3,7- bis(diethylamino)phenazinium chloride, 20, and 3,7-bis(diethylamino)-5- ethyl-phenazinium iodide, 21, which were also synthesized for this study. Incorporation of rigid peripheral tetrahydropyrazino ring systems in the pentacyclic azines 13, 14, and 15 are responsible for the improved fluorescence and singlet oxygen quantum yields relative to the tricyclic azines 20 and 21.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N950 | ChemSpider

Application of 6925-00-4, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 6925-00-4, Name is Quinoxaline-6-carboxylic acid, molecular formula is C9H6N2O2. In a Article，once mentioned of 6925-00-4

Structure-activity relationships on two novel potent cognition enhancing drugs, unifiram (DM232, 1) and sunifiram (DM235, 2), are reported. Although none of the compounds synthesised reached the potency of the parent drugs, some fairly active compounds have been identified that may represent new leads to develop other cognition enhancing drugs. An interesting result of this research is the identification of two compounds (13 and 14) that are endowed with amnesing activity (the opposite of the activity of the original molecules) and are nearly equipotent to scopolamine. Moreover, two compounds of the series (5 and 6) were found endowed with analgesic activity on a rat model of neuropathic pain at the dose of 1 mg/kg.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N814 | ChemSpider

Application of 2213-63-0, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2. In a Article，once mentioned of 2213-63-0

A series of novel 2-arylamino-3-(arylsulfonyl)quinoxalines was synthesized through a newly developed approach. All synthesized target compounds were screened for their cytotoxicities against cancer cell lines including PC3, A549, HCT116, HL60 and KB. Representative compounds with favorable cytotoxicities were tested for their PI3Kalpha inhibitory activities. Among the synthesized target compounds, 17 (PI3Kalpha IC50: 0.07 muM) displayed the most potent cellular activities (IC50 values of 0.14 muM, 0.07 muM, 0.95 muM and 0.05 muM against PC3, A549, HCT116 and HL 60, respectively).

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1601 | ChemSpider

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. name: 2,3-Dichloroquinoxaline. Introducing a new discovery about 2213-63-0, Name is 2,3-Dichloroquinoxaline

Herein, we report the synthesis of different steroidal thiazolo quinoxaline derivatives as antibacterial agents against Escherichia coli. Steroidal ketone thiosemicarbazones (4-6) were obtained from corresponding ketones (1-3) by refluxing with thiosemicarbazide. The thiosemicarbazones on reaction with 2,3-dichloroquinoxalines at 80 C gives 3beta-acetoxy-5alpha-cholestan-6-[thiazolo(4,5-b)quinoxaline-2-yl-hydrazone] (7), 3beta-chloro-cholestan-6-[thiazolo(4,5-b)quinoxaline-2-yl-hydrazone] (8), and 5alpha-cholestan-6-[thiazolo(4,5-b)quinoxaline-2-yl-hydrazone] (9). The structures of the compounds were evident by elemental, IR, 1H NMR and FAB mass spectral analyses. The antibacterial activities of these compounds were evaluated by disk diffusion method against the culture of E. coli and the results were compared with the standard drug amoxicillin. The results reveal that the compounds are better antibacterial agents as compared to amoxicillin. Among all the three compounds (7-9), compound 8 showed better zone of inhibition.

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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1399 | ChemSpider

Synthetic Route of 18514-76-6, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 18514-76-6, Name is 5-Nitroquinoxaline,introducing its new discovery.

[Cp?IrCl2]2 catalyses the cyclization of 2-alkynylanilines into indoles. A wide variety of substrates is tolerated. A reaction pathway involving intramolecular hydroamination is proposed.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N866 | ChemSpider

Reference of 59564-59-9, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 59564-59-9, 3,4-Dihydroquinoxalin-2(1H)-one, introducing its new discovery.

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof.The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, PDGFR, HER-1, HER-2, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

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Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N135 | ChemSpider

Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 2-Chloroquinoxaline, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 1448-87-9

A general and efficient protocol for direct C-H alkylation and acylation of N-heterocycles, using readily accessible carboxylic acids as radical precursors under visible-light irradiation without a photocatalyst and an additional acid additive, has been developed. This protocol provides expedient access to substituted N-heterocycles under mild and metal-free conditions. Mechanistic experiments indicate that this reaction proceeds through a visible-light-initiated radical chain propagation mechanism.

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Reference：
Quinoxaline – Wikipedia,
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