Extracurricular laboratory:new discovery of 2,3-Dichloroquinoxaline

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In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Recommanded Product: 2213-63-0, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 2213-63-0, name is 2,3-Dichloroquinoxaline. In an article,Which mentioned a new discovery about 2213-63-0

In this paper, we report the successful synthesis of new 2-phenyl-3-substituted furo/thieno[2,3-b]quinoxaline derivatives from 2-chloro-3-methoxyquinoxaline and 2-chloro-3-(methylthio)quinoxaline by a three-step approach. The Sonogashira coupling reaction of the title compounds with terminal alkynes afforded 2-methoxy-3-(phenylethynyl)quinoxaline and 2-(methylthio)-3-(phenylethynyl)quinoxaline in good to excellent yields. The iodocyclization of the resulting compounds using ICl in CH2Cl2 afforded 3-iodo-2-phenylfuro[2,3-b]quinoxaline and 3-iodo-2-phenylthieno[2,3-b]quinoxaline. The subsequent palladium-catalyzed Sonogashira, Suzuki, and Heck reactions of the resulting iodo compounds led to the formation of 2,3-disubstituded furo/thieno[2,3-b]quinoxaline in high yields. All compounds were fully characterized by FT-IR, mass, 1H NMR, and 13C NMR spectral data. The synthesized quinoxaline derivatives were also screened against the two bacterial strains Escherichia coli and Micrococcus luteus.

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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1272 | ChemSpider