Application In Synthesis of 2,3-Dichloroquinoxaline, New research progress on 2213-63-0 in 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world.2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2. In a article，once mentioned of 2213-63-0
The reaction of thiocarbohydrazide with carboxylic acids at the melting temperature allows an improved preparation of 5-substituted-4-amino-3-mercapto 1,2,4-triazoles 1a g. Compound 1a reacted with 2-bromopropionic acid to give acid derivative 2. The latter was reacted with a mixture of acetic anhydride and triethylamine to afford the mesoionic compound 3. Heating of compound 3 in ethanol gave the ester derivative 4, which on alkaline hydrolysis in methanol gave ketone derivative 5. Substituted 1,2,4-triazolo [3,4-b]-6H-1,3,4-thiadiazine 6h,i and 7 were synthesized by reaction of 1a with acetylacetone, ethyl acetoacetate and chloroacetamide. Heterocyclic systems 8 and 9 were prepared through the reaction of 1a with 2,3-dichloro-1,4-naphthoquinone and 2,3-dichloroquinoxaline. In addition, thenoyl isothiocyanate, thenoyl chloride, 2-thiophenecarbaldehyde, and p-chlorophenyl isocyanate reacted with compound 1a to afford 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole ring system 10, 11, and urea derivative 12. 1,2,4-Triazolo[3,4-b]-5H-pyrazole derivatives 14j,k were prepared through the reaction of compound 1a with 3-chloro-2,4-pentandione and ethyl-2-chloroacetoacetate. Compound 14j was treated with hydrazine to afford products 15, 16, and 17 depending on the type of hydrazine derivative and reaction conditions. Compound 19 was synthesized by refluxing of compound 14j with hydroxylamine hydrochloride to afford the corresponding oxime derivative 18 followed by treatment with thenoyl chloride.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Application In Synthesis of 2,3-Dichloroquinoxaline, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 2213-63-0, in my other articles.
Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1347 | ChemSpider